Placental Metastasis of a Chondromatous Osteosarcoma of the Scapular Belt
Chondromatous Osteosarcoma, Placental Metastasis
DOI:
https://doi.org/10.53555/bp.v8i2.2026Keywords:
pregnancy, placental metastasis, bones tumor, osteosarcomaAbstract
Pregnancy associated with cancer is rare and placental metastasis is exceptional. Breast cancer, cervix, melanoma and hematologic cancer are frequently associated with pregnancy. Bones and soft tissue tumor are rarely seen in pregnant woman. Actually, only disseminated cancer can induce placental metastasis. Although, growth factors are present during pregnancy, it seems that there is a defense mechanisms preventing neoplastic transplant within the placenta. However, gross can’t always find placental metastasis, so histological examination must be done for the diagnosis. We report a case of a 27 years old woman at 36 weeks of amenorrhea with scapular belt tumor discovered few months before her pregnancy. Due to a rapid evolution of the tumor a caesarean section was indicated. The tumor biopsy and the histological finding in the placenta showed a chondromatous osteosarcoma with placental metastasis. Our aims are to describe histological features of that type of metastasis and to compare it to other metastases of bones and soft tissue tumor.
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References
- Pentheroudakis G, Pavlidis N. Cancer and pregnancy: poena magna, not anymore. Eur J Cancer 2006;42(2):126–40.
- Zarkavelis G et al., Bone and soft tissue sarcomas during pregnancy: A narrative review of the literature, J Adv Res (2016), http://dx.doi.org/10.1016/j.jare.2016.01.003.
- Vinu Choudhary et al. Osteosarcoma in Pregnancy – A Rare case Report International Journal of Health Sciences & Research (www.ijhsr.org) Vol.7; Issue: 3; March 2017.
- Steffensen T, Gilbert-Barness E et al. human chorionic gonadotrophin producing epithelioid sarcoma metastatic to the placenta. Fetal and Pediatric Pathology, 27:282–291, 2008. DOI: 10.1080/15513810802448225.
- L. Dessolle, C. Dalmon, B. Roche, E. Daraï. Métastases placentaires de cancers maternels : revue de la littérature. La Revue Sage-femme 2007 ; 6 : 198-208.
- Epstein Shochet G, Tartakover Matalon S, Drucker L, Pomeranz M, Fishman A, Rashid G, et al. Hormone-dependent placental manipulation of breast cancer cell migration. Hum Reprod 2012; 27:73e88.
- Fox H. Non-trophoblastic tumors of the placenta, pathogy of the placenta. Philadelphia : Saunders ; 1978. p. 357-60.
- Salamon MA, Sherer DM, Saller DNJr, Metlay LA, Sickel JZ. Placental metastases in a patien twith recurrent breast carcinoma. AmJ Obstet Gynecol 1994 ; 171 : 573-4.]
- Figueiro-Filho et al. Sarcomas and Pregnancy. American Journal of Perinatology Reports Vol. 8 No. 4/2018.
