Development of a skin benign tumor, cancer and melanoma from the view point of morphofunctional zones

  • Yavisheva T. M. Head of scientific laboratory of mechanisms of stem cells regulation, Stock company “R-Pharm”, Russian Federation
  • Shcherbakov S.D. Professor of scientific laboratory of mechanisms of stem cells regulation, Stock company “R-Pharm”, Russian Federation
Keywords: morphofunctional zones, stem cells quantity, skin benign tumor, cancer, melanoma


Development  of a benign and malignant skin tumor in a morphofunctional zone in many respects depends on the quantity of cambial cells, which excite  an electric field at their division, due to  which  the inactive Src-kinase, participating in a formation of the cytoskeleton  and a differentiation,  is  expressed in cells. Decrease in cells number  to 8 leads to formation of a benign tumor, and up to 6 – to malignant as this quantity of cambial cells can't express enough inactive Src-kinase, necessary for  a normal cytoskeleton formation. The skin melanoma  can develop  without decrease in  cambial cells number due to sharp redistribution between shares of inactive and the active Src-kinase, thus the cytoskeleton formation and cell differentiation fall.


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How to Cite
T. M., Y., & S.D., S. (2018). Development of a skin benign tumor, cancer and melanoma from the view point of morphofunctional zones. International Journal For Research In Health Sciences And Nursing (ISSN: 2208-2670), 4(12), 01-05. Retrieved from