Malignant Peritoneal Mesothelioma: Report of a Rare and Challenging Surgical Case

Authors

  • A. A. Okomayin General Surgery Consultants, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria
  • A. E. Dongo General Surgery Consultants, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria
  • T. Azeke Consultant Pathologist, Irrua Specialist Teaching Hospital, Irrua
  • E. Tagar General Surgery Consultants, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria
  • C. Odion General Surgery Consultants, Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria
  • J. Okoeguale Consultant Gynaecologist, Irrua Specialist Teaching Hospital, Irrua
  • E. Ozah Consultant Urologist, Irrua Specialist Teaching Hospital, Irrua
  • S. Eluehike Consultant Radiologist, Irrua Specialist Teaching Hospital, Irrua
  • D. Lar Senior Anaesthetist, Irrua Specialist Teaching Hospital, Irrua

DOI:

https://doi.org/10.53555/hsn.v7i2.1530

Abstract

Malignant peritoneal mesothelioma is a rare tumour of mesothelial origin arising from the peritoneal linings and its incidence is second to pleural mesothelioma. Clinical presentation is often vague and non-specific posing great difficulty and delay in diagnosis. Thankfully, the biological behaviour and spread of the tumour makes local treatment with combine cytoreductive surgery and chemotherapy the standard first line treatment. We report a challenging case in a 50 year-old woman who presented with symptoms of 9 months duration and had cytoreductive surgery and adjuvant chemotherapy following histological confirmation of malignant peritoneal mesothelioma.

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References

Ahmed I, Koulaouzidis A, Iqbal J and Tan WC. Malignant peritoneal mesothelioma as a rare cause of ascites: a case report. Journal of Medical Case Reports 2008, 2:121.

Sterman DH: Advances in management of mesothelioma. Respirology 2005, 10:266-83.

Scripcariu V: Malignant peritoneal mesothelioma. Chirurgia (Bucur) 2006, 101:641-6.

Sudanthiram R, Vemulapalli C, Raja A, Santhosam R, Joseph J. Malignant peritoneal mesothelioma presenting as a complex omental lesion. Radiology Case Reports. 2012; 7 (2): 539.

Sugarbaker PH, Acherman YIZ, Gonzalez-Moreno S, Ortega-Perez G, Stuart OA, Marchettini P, Yoo D: Diagnosis and treatment of peritoneal mesothelioma: The Washington Cancer Institute experience. Semin Oncol. 2002; 29:51-61.

Zha BS, Flanagan M, Coulson C, Garvin KW. Difficult to indentify: malignant primary peritoneal mesothelioma. The American Journal of Medicine. 2015; 128 (11): 1191-94.

Broeckx G, Pauwels P. Malignant peritoneal mesothelioma: a review. Transl Lung Cancer Res. 2018; 7 (5): 537-42.

de Bree E, Christodoulakis M, Tsiftsis D. Malignant peritoneal mesothelioma treated by continuous hyperthermic peritoneal perfusion chemotherapy. Ann Oncol. 2000; 11 (6): 753-6.

Hassan R, Alexander R. Nonpleural mesotheliomas: mesothelioma of the peritoneum, tunica vaginalis, and pericardium. Hematol Oncol Clin North Am 2005; 19:1067–87.

Price B. Analysis of current trends in United States mesothelioma incidence. Am J Epidemiol 1997; 145:211-8.

Britton M. The epidemiology of mesothelioma. Semin Oncol. 2002; 29:18-25.

Boussios S, Moschetta M, Karathanasi A, Tsiouris AK, Kanellos FS, Tatsi K, Katsonos KH and Christodoulou DK. Malignant peritoneal mesothelioma: clinical aspects and therapeutic perspectives. Ann Gastroenterol. 2018; 31 (6): 659-69.

Boffetta P. Epidemiology of peritoneal mesothelioma: a review. Ann Oncol 2007; 18:985-90.

Marinaccio A, Corfiati M, Binazzi A, et al; ReNaM Working Group. The epidemiology of malignant mesothelioma in women: gender differences and modalities of asbestos exposure. Occup Environ Med. 2018; 75:254-262.

Park JY, Kim KW, Kwon HJ, Park MS, Gui Young Kwon GY, Jun SY, Yu ES. Peritoneal mesotheliomas: clinicopathologic features, CT findings, and differential diagnosis. AJR Am J Roentgenol 2008; 191:814-25.

Kim J, Bhagwandin S, Labow DM. Malignant peritoneal mesothelioma: a review. Ann Transl Med. 2017; 5 (11):236.

Cao SB, Jin S, Cao JY, Shen J, Zhang JW, Yu Y. Colonic invasion induced by malignant peritoneal mesothelioma. Int J Colorectal Dis 2014; 29:891-92.

Deraco M, Bartlett D, Kusamura S, et al. Consensus statement on peritoneal mesothelioma. J Surg Oncol 2008; 98:268-72.

Feldman AL, Libutti SK, Pingpank JF, et al. Analysis of factors associated with outcome in patients with malignant peritoneal mesothelioma undergoing surgical debulking and intraperitoneal chemotherapy. J Clin Oncol 2003; 21:4560-7.

Sugarbaker PH, Yan H, Grazi RV, Shmookler BM. Early localized peritoneal mesothelioma as an incidental finding at laparoscopy. Report of a case and implications regarding natural history of the disease. Cancer 2000; 89:1279-84.

Acherman YI, Welch LS, Bromley CM, et al. Clinical presentation of peritoneal mesothelioma. Tumori 2003; 89:269-73.

Manzini Vde P, Recchia L, Cafferata M, et al. Malignant peritoneal mesothelioma: a multicenter study on 81 cases. Ann Oncol. 2010; 21:348-53.

Kebapci M, Vardareli E, Adapinar B, Acikalin M. CT findings and serum ca 125 levels in malignant peritoneal mesothelioma: report of 11 new cases and review of the literature. Eur Radiol. 2003; 13:2620-6.

Lewin M, Arrive M, Wendum D et al. Imaging of peritoneal mesothelioma. J Radiol. 1996; 77: 649-56.

Attanoos RL, Gibbs AR. Pathology of malignant mesthelioma. Histopathology 1997; 30: 403-18

Levy AD, Arnaiz J, Shaw JC, et al. From the archives of the AFIP: primary peritoneal tumors: imaging features with pathologic correlation. Radiographics 2008; 28:583-607.

Husain AN, Colby T, Ordonez N, et al. Guidelines for pathologic diagnosis of malignant mesothelioma: 2012 update of the consensus statement from the International Mesothelioma Interest Group. Arch Pathol Lab Med. 2013; 137:647-67.

Lee M, Alexander HR, Burke A. Diffuse mesothelioma of the peritoneum: a pathological study of 64 tumours treated with cytoreductive therapy. Pathology 2013; 45:464-73.

Baratti D, Kusamura S, Martinetti A, et al. Circulating CA125 in patients with peritoneal mesothelioma treated with cytoreductive surgery and intraperitoneal hyperthermic perfusion. Ann Surg Oncol 2007; 14:500-508.

Yan TD, Deraco M, Elias D, et al; Peritoneal Surface Oncology Group. A novel tumornode-metastasis (TNM) staging system of diffuse malignant peritoneal mesothelioma using outcome analysis of a multi-institutional database. Cancer 2011; 117:1855-63.

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Published

2021-03-31

How to Cite

Okomayin, A. A. ., Dongo, A. E., Azeke, T., Tagar, E., Odion, C., Okoeguale, J., Ozah, E., Eluehike, S., & Lar, D. (2021). Malignant Peritoneal Mesothelioma: Report of a Rare and Challenging Surgical Case. International Journal For Research In Health Sciences And Nursing, 7(2), 01–07. https://doi.org/10.53555/hsn.v7i2.1530