A Descriptive Study on the Prevalence of Amoebic Liver Abscess in Eastern Afghanistan

Authors

  • Samiullah Sajjad Member of Radiology Department, Medical Faculty, Nangarhar University, Afghanistan
  • Hameedullah Safi Member of Microbiology Department, Medical Faculty, Nangarhar University, Afghanistan
  • Wahida Ahmady Member of Gyn/Obs Department, Medical Faculty, Nangarhar University, Afghanistan

DOI:

https://doi.org/10.53555/ans.v7i1.1485

Keywords:

Amoebic liver abscesses, E. histolytica

Abstract

Various studies suggest that Amoebic liver abscesses (ALA) are among the most common abscesses found in liver amoebic liver abscesses are caused by extra intestinal manifestation of Entamoeba histolytica (a protozoan parasite of the large intestine). This study was conducted to investigate the prevalence of ALA among Afghani patients according to various parameters described below. Patients and methods: the study was conducted on a total of 60 subjects (mean age 36 years) from November 2019 up to November 2020 admitted to the Nangarhar Regional Hospital and Dawoodzai curative Hospitals located at Eastern Afghanistan, Jalalabad city, diagnosed cases of liver abscesses. History, physical examination, and laboratory investigations were obtained. Ultrasound guided aspiration was done and samples were investigated in the study population. Pus culture were done for bacteria and direct microscopic investigation were also done for finding the trophozoites of E. Histolytica. Other causes of liver abscesses were excluded and amoebic abscesses were come in for investigation. Data were statistically analyzed by the use of Microsoft Excel program. Results. In the current study, 39 cases were diagnosed amoebic liver abscesses and included in the study. Majority of patients were of young age and male sex. Majority of them were from lower socioeconomic class (61.5%). Abdominal pain and fever were the most common presenting symptoms. According to lab findings ESR were elevated (84.1%), alkaline phosphatase (76.9%), WBC elevation (84.6%) and liver transaminases were elevated in 36% of these patients.  The abscesses were predominantly in right lobe (71.7%) and solitary (71.7%). Abscess size in ultrasound ranged from 3cm to 14cm. Right lobe was predominantly involved in amoebic abscesses but left lobe involvement and diffuse involvement was also present.The results of this study show that amoebic liver abscesses are commonly presenting in young aged patients of male sex, of low socioeconomic class having right lobe solitary amoebic liver abscess.

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Published

2021-01-31

How to Cite

Sajjad, S., Safi , H., & Ahmady, W. . (2021). A Descriptive Study on the Prevalence of Amoebic Liver Abscess in Eastern Afghanistan. International Journal For Research In Applied And Natural Science, 7(1), 01–07. https://doi.org/10.53555/ans.v7i1.1485

Issue

Vol. 7 No. 1 (2021): International Journal For Research In Applied And Natural Science (ISSN: 2208-2085)

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