Preliminary Phytochemical and Antibacterial Screening of Acanthospermum hispidium

Authors

  • Catherine O. Attah Department of Chemistry, School of Sciences, Federal College of Education, Islamabad, Pakistan
  • Ibrahim Sunday Department of Chemistry, School of Sciences, Federal College of Education, Islamabad, Pakistan
  • Dayyibatu M. Lamido Department of Environmental Science, College of Environmental Studies, Kaduna Polytechnic, PMB 2021, Kaduna, Nigeria
  • Abdulkadir R. Salisu Department of Environmental Science, College of Environmental Studies, Kaduna Polytechnic, PMB 2021, Kaduna, Nigeria
  • Ahmad I. Muhammad Department of Biochemistry, Kano University of Science and Technology, Wudil, Kano State - Nigeria
  • Isa Yunusa Department of Biochemistry, Kano University of Science and Technology, Wudil, Kano State - Nigeria

DOI:

https://doi.org/10.53555/ans.v2i1.121

Keywords:

Phytochemicals, antibacterial,, Acantospermum hispidum

Abstract

Acantospermum hispidium is a medicinal plant commonly known as ‘‘Kashin yawo’’ in northern
Nigeria. The leaves are used locally for the treatment of acute fever, cough, diarrhea, dysentery,
typhoid and pneumonia. The present research was conducted to investigate the preliminary
phytochemical compounds and antibacterial effect of Acantospermum hispidum plant on clinical
bacterial isolates of Escherichia coli and Staphylococcus aureus. The plant was subjected to
series of phytochemical screening tests and its potency was tested against E. coli and S. aureus
using paper - disc diffusion and broth dilution techniques. Aqueous extract had activity only at
its highest concentration (80 mg/ml), while the ethanolic extract had more pronounced activity
for both bacterial isolates compared to N- hexane, petroleum ether, chloroform and aqueous
extracts. Phytochemical analysis of Acantospermum hispidium plant extracts indicated the
presence of tannins, saponins, flavonoids, and alkaloids which contain chemical constituents of
pharmacological importance. Glycoside was absent in all the extracts.

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References

Adoum, O. A., Akinniyi, J. A., and Omar.A. (1997).The effect of geographical location on the antimicrobial activities and trace element concentration in the root of Calotropis procera (Ait.)R. Br.Annals of Brono13(14),199-207.

Akintobi, O. A., Onoh C. C., Ogele J. O., Idowu,A. A., Ojo O. V. and Okonko,I. O. (2013).Antimicrobial activity of Zingiber officinale (Ginger) extract against some selected pathogenic bacteria, Nature of science, 11(1).

Anani, K. Hudson, J. B., de Souze, C., Akpagana K., Tower, GHN. Amason J. T. Gbeassor, M. (2000). Investigation of medicinal plant of Togo for Antiviral and Antimicrobial activity. Pharm. Biol.38 (1).40-45.

Bibitha, B., Jisha, V. K., Salitha, C. V., Mohan, S. and Valsa, A. K. (2002).Antibacterial activity of different plant extracts: A short communication Indian Journal of Microbiology.42: 361-363.

Cheesbrough, M. (2002).Distribution laboratory practice in tropical countries. Cambridge University Press, London. 2: 137-140.

Choudhary,M.,Kumar,V.,Malhotra, H. and Singh, S. (2015). Medicinal plants with potential anti-arthritic activity, J Intercult Ethnopharmacol,4(2): 147-179.

Edewor, T., Olajira, A. (2011).Two flavones from Acantospermum hispidium D.C and their antibacterial activity.Int. J. Org. Chem.1 (3): 132-141.

Ellof, J. N. (1998).Which extract should be used for the screening and isolation of antimicrobial components from plants?Ethanopharmacologia60: 1-6.

Fatope, M. O, Ibrahim H. and Takeda, Y. (1993).Screening of higher plant reputed as pesticides using the brine shrimplethality assay.International journal of pharmacognosy31:250-254.

Fleischer,T. C., Ameade, E. P., Sawer I. K. (2003). Antimicrobial activity of leaves and flowering top of Acanthospermum hispidiumFitoteerapia.74 (1-2): 130-132.

Gafon, H.,Bero, J.,Alembert, T., Tchinda A. T., Fernard, G., Gbenou, J., Moudachirou M., Michel, F.M. andQuetin-Leclercq, J. (2012). Antiparasitic activities of two sesquiterpenic lactones isolated from Acanthospermum hispidium D. C. J.Ethnopharmacol.141: 411-417.

Hoffman, B. R., Delasalas, H., Blanco, K. Wiederhold, N., Lewis, R. E.andWilliams, L. (2004). Screening of Antibacteria and Antifungal activities of ten Medicinal plants from Ghana.Pharm. Biol.42 (1): 13-17.

Kala C. P., Farooquee N. A. and Dhar U. (2004).Prioritization of medicinal plants on the basis of available knowledge, existing practices and use value status in Uttaranchal, India. Biodiversity and conversation. 13:453-469.

Kamanzi, A. K., schamid C., Brun R., Kone M. W. and Traore, D. (2004). Antitrypanosomal and Antiplasmodial activities of Medicinal plants from Cote D’ivoireJ. Ethnopharmacol. 90 (2-3): 221-227.

Kamanzi, A. K.,Kone, M., Terreaux, C., Traore, D., Hostettmann K., Dosso M. (2002). Evaluation of the Antimicrobial potential of medicinal plant from the Ivory Coast Phytother. Res.16: 497-502.

Kirby, W. M., Bauer, A. W., Sherris,J. C. and Tutcch, M. C. (1966).Antibiotic susceptibility testing by a standardized single disc method.American journal of clinical pathology45:493-496.

Lutterodt, G. D., Ismail, A., Bashier, R. H. and Baharudin, H. M. (1994): Antimicrobial effects of Psidium guajava extract as one mechanism of its anti-diarrhoeal action.Malaysian Journal of Medical sciences6,17-20.

Mann, A. Gabate M. Umar, N. A. (2003).Medicinal and Economical plants in Nupeland Jube-Evans books and publication, Bida, Niger State.Mukhtar M.D and Okafor, M. C. (2002).Antibacteria activity of Gueria senegalensisjour. EmpericResearch: 1 (2),166-72.

Nair, A.G., Subramanan, S.S., Bohlmann, F., Schoneweiss, S., Mabry, T. J. (1976).New diterpene galactoside from Acanthospermun hispidium. Phytochemistry.15 (11),1776-1778.

Okoli R.I, Aigbe O., J.O, Mensah J.K, (2007), Medicinal Herbs Used for Managing Some Common Ailments among EsanPeople of Edo State, Nigeria, Pakistan Journal of Nutrition 6 (5): 490-496.

Oyi, A. R., Onaolapo, J. A., and Adigun, J. O. (2002): Phytochemical and antimicrobial screening of the Latex of Jatropha curcas Linn (Euphorbiaceae).Journal of phytomedicine and therapeutics1(1-2),63-74.

Oyi, R. A., Onaolapo, J. A., Haruna, A. K. and Morah, C.O. (2007).Antimicrobial screening and stability studies of crude extracts of Jatropha curcas Linn Latex (Euphorbiaceae).Nigeria Journal of pharmaceutical sciences6(2),14.

Poongothai, A., Sreena, K.P., Sreejith, K., Uthiralingam M. and Annapoorani, S. (2011). Preliminary phytochemicals screening of ficus racemosa linn back, International Journalof Pharmaceutical and Biological Sciences vol. 2 issue 2, ISSN 0975-6299

Salihu, L. and Garba, S. (2008).Preliminary investigation of the bioactive constituents of some medicinal plants.Biological and Environmental sciences Journal for the Tropics. 5(1),164-168.

Saleh, S. B., Ibrahim,T., Salisu,A.R., Shaida,S.S.,Jibril, H.,Tela, I. H., Abdullahi, S.S., Adekemi, E.A., Kabir, H.M., Bala, I. andSuleiman A. (2015)Antitrypanosomal Activity of Leaf Extracts of Acalypha Wilkesiana.International Journal of Life Science and Engineering Vol. 1, No. 3, 2015, pp. 114-119.

Sanon, S., Azas, N., Gasquest, M., Olivier, E.,Mahrou, V., Baro, N., Cuzin-Quattara, N., Traore, A. S., Esposito, F., Balasard, G., Timon-David, P. (2003). Antiplasmodium activities of alkaloid extract from pavetta crassipe and Acanthospermum hispidium, two plants use in traditional Medicine in Bukinsfaso. Paracitol.Res. 90 (4),314-317.

Sofowora, A. (1993).Medicinal plant and traditional mecicine in Africa. Spectrum books Limited, Ibadan, Nigeria. 220-224.

Summerfield A. Keil G. M. Menttenlerter T. C., Rziha, J. H. Saalmuller,A. (1997).Antiviral activity of an extract from leaves of the Tropical plant Acanthospermum hispidium Antivi. Res.36: 55-62.

The Ayurvedic Pharmacopoeia of India. (2004).Government of India Ministry of Health and Family Welfare. Part 1, vol. 1.Trease,G. E. and Evans, W. C. (1989).Pharmacognosy 1stedition. Amadu Bello University press Limited, Zaria, Nigeria.188-198.

Yusha’u, M., Bukar, A. and Balarabe, A. I. (2008).Prevalence and sensitivity of enterobacterial isolates from patients with urinary tract infections to Acalypha wilkiseniaextracts.Biological and environmental sciences Journal for the tropics.5(3),72-76.

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Published

2016-01-31

How to Cite

Attah, C. O., Sunday, I., Lamido, D. M., Salisu, A. R., Muhammad, A. I., & Yunusa, I. (2016). Preliminary Phytochemical and Antibacterial Screening of Acanthospermum hispidium. International Journal For Research In Applied And Natural Science, 2(1), 101–112. https://doi.org/10.53555/ans.v2i1.121

Issue

Vol. 2 No. 1 (2016): International Journal For Research In Applied And Natural Science

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Articles

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