PRIMITIVE MALIGNANT GERM CELL TUMORS OF THE OVARY: ABOUT 11 CASES AND LITERATURE REVIEW

Authors

  • Volahasina Francine Ranaivomanana University hospital of Ravoahangy Andrianavalona, Pathology Department
  • Holy Tiana Andrianjafitrimo University hospital of Ravoahangy Andrianavalona, Pathology Department
  • Haingo Voahangy Rabetafika Ranaivoson University hospital of Ravoahangy Andrianavalona, Pathology Department
  • Nantenaina Soa Randrianjafisamindrakotroka University hospital of Ravoahangy Andrianavalona, Pathology Department

DOI:

https://doi.org/10.53555/bp.v9i2.2191

Keywords:

germ cell, malignant, ovary, histology

Abstract

Malignant germ cell tumors of the ovary are rare entities. They mainly affect young patients and can threaten the functional prognosis.

We carried out a retrospective study of 11 cases of primary malignant germ cell tumors of the ovary, diagnosed at the paraclinical training and research unit in Pathological Anatomy and Cytology of the CHU/JRA, within a period of 10 years, from January 2010 to December 2019. The ages of these patients varied from 2 to 63 years old with an average of 30,5 years old. In the majority of cases (7 cases), radical treatement was achieved. The guiding clinical information was in all cases an abdominopelvic mass. The right side was the most affected (6/11) and one case was bilateral. The most common histological type was dysgerminoma (4/11).

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References

. Quirk JT, Natarajan N. Ovarian cancer incidence in the United State, 1992-1999. Gynecol Oncol 2005 ; 97(2):519–

. Surratt JT, Siegel MJ. Imaging of pediatric ovarian masses. Radiographics, 1991; 11: 533 - 48.

. Ray-Coquard I, Pautier P, Pujade-Lauraine E, Méeus P, Morice P, Treilleux I, Duvillard P, Alexandre J, Lhommé

C, Selle F, Guastalla JP. Les tumeurs rares de l’ovaire : stratégies thérapeutiques en 2010, observatoire

francophone des tumeurs rares de l’ovaires et émergence des centres de références. Bull Cancer 2010, 97 (1) : 123

– 35.

. Tewari K, Cappuccini F, Disaia PJ, Berman ML, Manette A, Kohler MF. Malignant germ cell tumors of the ovary.

Obstetric and gynecolgy 2000 ; 98 (1) : 128 – 33.

. Mamouni N, Saadi H, Erraghay S, Bouchikhi C, Banani A. Tumeurs rares de l’ovaire : à propos de 11 cas de

tumeurs non épithéliales malignes de l’ovaire. Pan African Medical Journal. 2015; 20:174.

. Kurman RJ, Norris HJ. Embryonal carcinoma of the ovary: a clinicopathologic entity distinct from endodermal

sinus tumor ressembling embryonal carcinoma of the adult testis. Cancer 1976; 38: 2420-33.

. Gueye A, Narducci F, Baranzelli M-C, Collinet P, Farine O, Fournier C, Vinatier D, Leblanc E. Tumeurs

germinales de l’ovaire. A propos de 36 cas. Gynécologie Obstétrique & Fertilité 2007 (35) 406 –419.

. Yamaoka T, Togashi K, Koyama T, Fujiwara T, Higuchi T, Iwasa Y , et al. Immature teratoma of the ovary:

correlation of MR imaging and pathologic findings Eur. Radiol. 2003; 13: 313-319.

. Kurman RJ, Norris HJ. Malignant germ cell tumors of the ovary. Hum Pathol 1977; 8(5): 551 - 64.

. Tavassoli FA, Devilee P. Tumors of the ovary and peritoneum. In: Tavassoli FA, Devilee P, eds. World health

organization of tumors pathology and genetics of tumors of the breast and female genital organs. Lyon: IARC

Press, 2003: 113 – 97.

. Brammer HM, Buck JL, Hayes WS, Sheth S, Tavassoli FA. From the archives of the AFIP, malignant germ cell

tumors of the ovary: radiologic-pathologic correlation; radiographics. 1990 ;10;715.

. Berek JS, Hacker NF. Non epithelial ovarian and fallopian tube cancers. In: Barek J, Hacker NF, eds. Practical

Gynecologic Oncology. Philadelphia, PA: Lippincott Williams & Wilkins, 2005:511–541.

. Gershenson DM, del Junco G, Silva EG, et al. Immature teratoma of the ovary. Obstet Gynecol. 1986;68:624–629.

. Querleu D, Gladieff L, Delannes M, Mery E, Ferron G, Rafii A. Preservation of fertility in gynaecologic cancers.

Bull Cancer 2008 ; 95 : 487-94.

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Published

2023-02-23

How to Cite

Ranaivomanana, V. F., Andrianjafitrimo, H. T. ., Ranaivoson, H. V. R., & Randrianjafisamindrakotroka, N. S. (2023). PRIMITIVE MALIGNANT GERM CELL TUMORS OF THE OVARY: ABOUT 11 CASES AND LITERATURE REVIEW. International Journal For Research In Biology & Pharmacy, 9(2), 1–2. https://doi.org/10.53555/bp.v9i2.2191

Issue

Vol. 9 No. 2 (2023): International Journal For Research In Biology & Pharmacy (ISSN: 2208-2093)

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