Vol 5 No 8 (2019): International Journal For Research In Biology & Pharmacy (ISSN: 2208-2093)
Articles

Investigation of Thrombocytopenia in Patients of Malaria

Dr. M. Arif. Rahmani
Bio
Dr. Gulaqa. Sadat
Bio
Published August 23, 2019
Keywords
  • Malaria,
  • Plasmodium falciparum,
  • Plasmodium vivax,
  • thrombocytopenia
How to Cite
Dr. M. Arif. Rahmani, & Dr. Gulaqa. Sadat. (2019). Investigation of Thrombocytopenia in Patients of Malaria. International Journal For Research In Biology & Pharmacy (ISSN: 2208-2093), 5(8), 18-23. Retrieved from https://gnpublication.org/index.php/bp/article/view/1083

Abstract

Protozoan parasites of the genus Plasmodium cause malaria, a devastating disease prevalent across tropical regions around the world. In the year 2016, more than 216 million clinical cases and 445,000 deaths were reported across 91 countries worldwide This scientific research has started and ended in the period of 2 years, conducted from 2/1/2018 to 5/8/2019 in the infectious wards/branches of the Nangarhar medical faculty’s. Materials and Methods: We conducted this study to find out the frequency and the degree of thrombocytopenia in patients with malaria. In our study, 180 patients with malaria positive were investigated with platelet count. Results: In the study group of 180 patients: 101 (56.11%) were positive for Plasmodium vivax, 70 (38.88%) were positive for P. falciparum and 9 (5.00%) had mixed infection with both P. vivax and P. falciparum. Out of 101 cases detected with vivax malaria, 77 cases had thrombocytopenia. Out of 70 cases detected with falciparum malaria, 54 cases had thrombocytopenia. Among 9 cases of mixed infection, 6 cases had thrombocytopenia. Conclusions: Presence of thrombocytopenia in a patient with acute febrile illness in the tropics increases the possibility of malaria. The above finding can have therapeutic implications in context of avoiding unnecessary platelet infusion in malaria patients.

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