Is there an association between helicobacter pylori infection and dyslipidemia?
Various studies suggest that H. pylori infection is associated with atherosclerosis, but its mechanism is still unclear. This study was conducted to investigate the association between Helicobacter Pylori (H. pylori) infection and the lipid profile among elderly Afghani population.
Patients and methods: the study was conducted on a total of 300 subjects (mean age 61.2 7.6yr) from January 2018 up to March 2019. Serum anti-Helicobacter pylori antibody titer and serum lipid profile were assessed in the study population, data were statistically analyzed by SPSS version 16.P value < 0.05 were considered significant.
Results in the current study, 62% of the case were serologically positive for H. pylori. among male cases, the level of low density lipoprotein (LDL) was higher in H. pylori positive patients in comparison with H. pylori negative patients (p = 0.03); although level of triglyceride (TG) was higher and the level of high density lipoprotein (HDL) was lower in H. pylori positive patients; but was not statistically significant difference among TG, HDL in H Pylori positive and negative cases. Among female cases, the negatives (P = 0.001); but here was no significant difference between H. pylori positive and negative cases regarding the level of LDL and HDL.
Conclusion; The results of this study shows that the LDL level was high among male H. pylori positive cases and TG level was low in H. pylori positive female cases.
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