The Tuberculosis of Female Genital Tract: About 5 Cases and Review of Literature

Authors

  • Volahasina Francine Ranaivomanana Department of Pathology, Joseph Ravoahangy Andrianavalona University Hospital, Antananarivo, Madagascar
  • Holy Tiana Andrianjafitrimo Department of Pathology, Joseph Ravoahangy Andrianavalona University Hospital, Antananarivo, Madagascar
  • Haingo Voahangy Rabetafika Ranaivoson Department of Pathology, Joseph Ravoahangy Andrianavalona University Hospital, Antananarivo, Madagascar
  • Nantenaina Soa Randrianjafisamindrakotroka Chairman at the Department of Pathology, Medical School of Antananarivo, Madagascar

DOI:

https://doi.org/10.53555/bp.v7i11.1916

Keywords:

Tuberculosis, Woman, Genital, Anatomic Pathology, Madagascar

Abstract

ABSTRACT

Female genital tuberculosis is a rare condition, affecting mostly young women. It is mainly seen in developing countries. The aim of this study is to describe the epidemiological and pathological aspects of female genital tuberculosis.This is a retrospective and descriptive study of genital tuberculosis diagnosed in women, over a period of 5 years and half, from January 2014 to June 2019. We included the locations on the genital tract and excluded the other locations.We recruited 369 cases of extra-pulmonary tuberculosis and selected 5 cases of female genital location. The age of the patients ranged from 14 to 48 years, with an average of 28.8 years. The locations were cervical (2/5), uterine (2/5) and tubal (1/5). The morphological aspect was typical with epithelioid granulomas, Langhans giant cells with caseous necrosis in 2 cases, without caseous necrosis in 3 cases. In one of the cervical cases, there was associated with high-grade intraepithelial neoplasia. Female genital tuberculosis is a rare form of extra-pulmonary tuberculosis. The diagnosis is histological. The morphological aspect can sometimes pose differential diagnoses requiring a confrontation with the clinic or other specific examinations.

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Author Biographies

Volahasina Francine Ranaivomanana, Department of Pathology, Joseph Ravoahangy Andrianavalona University Hospital, Antananarivo, Madagascar

 

 

Nantenaina Soa Randrianjafisamindrakotroka, Chairman at the Department of Pathology, Medical School of Antananarivo, Madagascar

 

 

References

WHO. WHO global tuberculosis report 2016. [accessed on April 27, 2017]. Available from: http://www.who.int/tb/publications/global_report/en/

Chowdhury NN. Overview of tuberculosis of the female genital tract. J Indian Med Assoc 1996;94: 345-6.

Rakotomahenina H, Andrianampy HA, Rakotoson JL, Rabarijaona M, Solofomalala GD, Brun JL. La tuberculose génitale découverte devant une stérilité : deux premiers cas observés au CHU Fianarantsoa Madagascar. Médecine et Santé Tropicales 2015 ; 25 : 331-3.

Ravelosoa E, Randrianantoanina F, Rakotosalama D, Andriampanalinarivo R, Rakotomalala C, Rasolofondraibe A, Breda Y, Rakotobe P. La tuberculose génitale chez la femme : à propos de 11 cas suivis à Antananarivo, Madagascar. Bull Soc PatholExot, 2007, 100, 1, 30-1.

Efared B, Sidibé IS, Erregad F, Hammas N, Chbani L, Fatemi HE. Femal genital tuberculosis: a clinicopathological report of 13 cases. Journal of Surgical Case Reports, 2019;3, 1–4.

Kumar S. Female genital tuberculosis. In: Sharma SK, Mohan A, editors. tuberculosis. 3rd ed. Delhi: Jaypee Brothers Medical Publisher Ltd.; 2015. p. 311–24.

Sharma JB. Current diagnosis and management of female genital tuberculosis. J ObstetGynaecol India. 2015;65:362–71.

Singh N, Sumana G, Mittal S. Genital tuberculosis: a leading cause for infertility in women seeking assisted conception in North India. Arch GynecolObstet. 2008;278:325–7.

Neonakis IK, Spandi dos DA, Petinaki E. Female genital tuberculosis: a review. Scand J Infect Dis 2011; 43:564 – 72.

Hassoun A, Jacquette G, Huang A, Anderson A, Smith MA. Femal genital tuberculosis: uncommon presentation of tuberculosis in the United States. The American Journal of Medicine (2005) 118, 1295-9.

Neonakis IK, Spandi dos DA, Petinaki E. Female genital tuberculosis: a review. Scand J Infect Dis 2011; 43:564 – 72.

Baxi A, Neema H, Kaushal M, Sahu P, Baxi D. Genital tuberculosis in infertile women: Assessment of endometrial TB PCR results with laparoscopic and hysteroscopic features. J ObstetGynecolIndia. 2011;61:301–6.

Mondal SK. Histopathologic analysis of female genital tuberculosis: A fifteen-year retrospective study of 110 cases in Eastern India. Turk J Pathol. 2013;29:41–5.

Altchek A, Deligdisch L, Kase N. Diagnosis and management of ovarian disorders.San Diego (CA): AcademicPress; 2003.

WHO. Guidelines for treatment of tuberculosis. Geneva: WHO; 2010.

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Published

2021-11-30

How to Cite

Ranaivomanana, V. F., Andrianjafitrimo, H. T. ., Ranaivoson, H. V. R., & Randrianjafisamindrakotroka, N. S. (2021). The Tuberculosis of Female Genital Tract: About 5 Cases and Review of Literature. International Journal For Research In Biology & Pharmacy, 7(11), 05–09. https://doi.org/10.53555/bp.v7i11.1916

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