A New Process of Standardization for Promising Antioxidant Herbal Formulation of Momordica charantia Linn. (Family- Cucurbitaceae ) by Using Several Parameters and Analytical Techniques

Authors

  • Subhajit Ghosh Sarada Vilas College Of Pharmacy, Mysore, India
  • Hanumanthachar Joshi Sarada Vilas College Of Pharmacy, Mysore, India
  • P. N. Murthy Royal College of Pharmacy and Health Sciences, Berhampur, India
  • Dhirendra Kumar Tarai K.V.Virani Institute of Pharmacy and Research Centre, Badhada, Gujarat, India

DOI:

https://doi.org/10.53555/bp.v2i4.134

Keywords:

Herbal Drug,, Herbal Raw Material,, Momordica charantia Linn,, Herbal Formulation, Standardization, Chromatographic Fingerprint.

Abstract

Since the age of ancient times to till date herbal drugs have been used for the treatment of a wide range of diseases. In the recent time more number of people throughout the world is very much concentrating to use of herbal products in the health care system for that herbal products have played a key role in the world health system. Now the people of the world wide need some alternative medicine has a resulted in the growth of the markets of herbal products and interest in our traditional system of medicine.In modern system of Herbal Drug Technology is used for converting raw herbal materials or plant products or food products in to a specific formulation which is use as a medicine, where for this processing, standardization and quality control is necessary with the proper integration of modern technology with the help of Scientific and Traditional knowledge is important. In order to prove constant and promising composition of herbal preparation for here Antioxidant activity, adequate parameters and Analytical methods that have to be applied such as Thin layer Chromatography (TLC), High Performance Liquid Chromatography (HPLC) etc.

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References

Manach C, Scalbert A, Morand C, Remesy C, Jimenez L. 2004.Polyphenols: food sources and bioavailability. Am J Clin Nutr ;79:727-47.

Rivera, Gilberto.1941.“Preliminary Chemical and Pharmacological Studies on ‘Cudeamor.’” Momordica charantia L.(Part I). Amer. J.Pharm., 113(7) , 281-296 .

Sharma, V.N., R.K Sogani and R.B. Arora.1962.“Some Observations on Hypoglycemic Activity of Momordica charantia.”Ind. Jour. Med. Res., 48(4), 471-477.

Takemoto, D.J.C. Villa and R. Kresie. 1982.“Purification and Characterization of a Cytostatic Factor from the Bitter Melon Momordica charantia.” Preparative Biochemistry, 12(4), 355-375.

Lotlikar, M.M. and Dr. M.R. Rajarama Rao.1962.“Note on a Hypoglycemic Principle Isolated from the Fruits of Momordica charantia.” J. University of Bombay, 29, 223-224.

Dunrad, E., E.V. Ellington, P.C. Feng, L.J. Haynes, K.E. Magnus and N. Philip. “Simple Hypotensive and Hypertensive Principles from Some West Indian Plants.”

Baldwa, V.S., C.M. Bhandari. A Pangaria and R.K. Goyal. 1977.“Clinical Trials in Paitiens with Diabetes Mellitus on an Insulin-like Compound Obtained from Plant Source.” Upsala J. Med. Sci., 82, 39-41.

Veseley, David L., W.R. Graves, T.M. Lo, M.A. Fletcher and G.S. Levey. 1977.“Isolation of a Granylate Cyelase Inhibitor from the Balsam pear (Momordica charantia Abreviata).” Biochem, And Biophys. Res. Comm., 77(4), 1294-1299.

Lin, J.Y., M.J. Hou and O.C. Chen. 1978.“Isolation of Toxic and Non-Toxic Lectins from the Bitter Pear Melon Momordica charantia Linn.’ Toxicon, 16, 653-660.

Li, S.S.L1980. “Purification and Partial Characterization of Two Lectins from Momordica charantia .” Experentia, 36, 524-527.

Sucrow, W. Tetrahedron Lett.1965, Sterol glycoside and a new dstigma stadienol from Momordicacharantia,26, 2217.

.Ulubelen, A. and U. Sankawa.1979“Steroids and Hydrocarbons of the leaves of Momordica charantia.” Rev. Latino-amer. Quim., 10, 171-173.

WHO. The World Medicines Situation, Traditional Medicines: Global Situation, Issues and Challenges, World Health Organization,Geneva; 2011.

Mukherjee PK, 2006.Wahile A. Integrated approaches towards drug development from Ayurveda and other Indian system of medicines. J Ethnopharmacol.; 103:25–35.

MacLennan AH, Wilson DH, Taylor AW.1996.Prevalence and cost of alternative medicine in Australia. Lancet; 347: 569-573.

Tapsell LC, Hemphill I, Cobiac L, et. al.2006.Health benefits of herbs and spices: the past, the present, the future. Med J Aust; 185 (4 Suppl): S4-24.

Mukherjee PK,2009 Houghton PJ. The worldwide phenomenon of increased use of herbal products: opportunity and threats. Evaluation of Herbal Medicinal Products-Perspectives on Quality, Safety and Efficacy. Pharmaceutical Press, Royal Pharmaceutical Society of Great Britain, pp. 3–12.

Robbers JE, Tyler VE. 1999.Tyler’s Herbs of Choice: The Therapeutic Use of Phytomedicinals. The Haworth Herbal Press, Inc., New York. pp 124-158.

Anonymous. The Ayurvedic Pharmacopoeia of India. Part-1, vol.-I, 1stedition. The Controller of Publication, Delhi; 1990.

Sharma DC.2000. India raises standards fortraditional drugs. Lancet; 356:231.21.Patwardhan B.1996. A method of treating musculoskeletal disease and a novel composition thereof. US Patent No. 5494668.

Singh K, Chandar R, Kapoor NK.1998.Guggulsterone, a potent hypolipidaemic, prevents oxidation of low-density lipoprotein. Phytother Res.; 11:291–4.

Indian Council of Medical Research. Flexible dose open trail of Vijayasar in cases of newly diagnosed non-insulin dependent diabetes mellitus. Indian J Med Res., 1998; 108:24–9.

Bensky A, Ellis A, Barolet R. 2009.Chinese Herbal Medicine: Formulas and Strategies, Eastland Press, Seattle, Wash, USA, 2ndedition;.

PK Mukherjee, NK Nema, P Venkatesh, et al.2012Changing scenario for promotion and development of Ayurveda–way forward,” J Ethnopharmacol; 143(2): 424–434.

KB Lee, KH Shin, WS Wan.1984.Central nervous depressant and antiinflammatory activity of piperine. Arch Pharmacol Res; 1:127–132.

Gautam V, Raman RMV, Ashish K..2003Exporting Indianhealthcare (Export potential of Ayurveda and Siddhaproducts and services) Road beyond boundaries (The caseof selected Indian healthcare systems).Gautam V, RamanRMV, Ashish K. (eds.) Export-Import Bank of India;Mumbai:p 4–54.

Sagar Bhanu PS, Zafar R, Panwar R,2005. Herbal drug standardization. The Indian Pharmacist; 4(35):19-22.

Tasneef Ahmad, Swatantra Bhadur Singh, Shivshankar Pandey.Dec-2013.Phytochemical Screening and physicochemical parameters of crude drugs: A Brief Review. International Journal of Pharma Research & Review.2(12):53-60.

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Published

2016-04-30

How to Cite

Ghosh, S., Joshi, H., Murthy, P. N., & Tarai, D. K. (2016). A New Process of Standardization for Promising Antioxidant Herbal Formulation of Momordica charantia Linn. (Family- Cucurbitaceae ) by Using Several Parameters and Analytical Techniques. International Journal For Research In Biology & Pharmacy, 2(4), 01–31. https://doi.org/10.53555/bp.v2i4.134