Vol 5 No 9 (2019): International Journal For Research In Biology & Pharmacy (ISSN: 2208-2093)
Articles

Heparin sodium uses in children's cataract surgery

Assistant professor Dr Abdul Basir Safi
Lecturers of Ophthalmology department, Medical Faculty, Nangarhar University
Teaching assistant Dr Ibrarullah Rahimi
Lecturers of Ophthalmology department, Medical Faculty, Nangarhar University
Published September 1, 2019
Keywords
  • Heparin,
  • Congenital cataract,
  • Vision,
  • Anterior chamber,
  • Posterior capsule opacity
How to Cite
, A. professor D. A. B. S., & Teaching assistant Dr Ibrarullah Rahimi. (2019). Heparin sodium uses in children’s cataract surgery. International Journal For Research In Biology & Pharmacy (ISSN: 2208-2093), 5(9), 16-23. Retrieved from https://gnpublication.org/index.php/bp/article/view/1102

Abstract

After cataract extraction of the child's eye, the vision is reversed (decreases), because after surgery Fibrin is found in anterior chamber, for prevention of formation fibrin we use heparin and does not decrease the vision. The aim of this research is to study of use and non-use of heparin in children eye surgery, differentially. This is case control study conducted on sartan 1397 to jawza 1398 within one year on 30 patients in University Teaching Hospital Eye ward.

In group A, there were 14 eyes that used heparin sodium in surgery and in group B there were 16 eyes that had surgery with no heparin sodium uses. Statistical analysis of the study revealed that the odds ratio is 7.714 that is seven times greater use of heparin with improvement and better result. the p valve is 0.0256 which is very close to the fact and Z statistic is 2.233.

In research group A in which we used heparin in cataract surgery 2 eyes 14, 28% had a posterior capsule density, one patient had a posterior synechia that gave 7, 14%, and two patients who had hyphaemia that gave 14,28%,that mean anterior chamber had blood . In B group three eyes pupil completely close mean had occulosive pupil 18, 75%.

In the study 14 female gender 46, 66% and 16 male genders 53, 33 % were in observation. And research has shown that the use of heparin to prevent the complications of cataract surgery in children is most likely having good result.

Downloads

Download data is not yet available.

References

1. Henning A, Kumar J, Yorston D, Foster A. Sutureless cataract surgery with nucleus extraction: Outcome of a prospective study in Nepal. Br J Ophthalmol. 2003; 87: 266–70. YASIR IQBAL, et al 240 Vol. 30, No. 4, Oct – Dec, 2014 Pakistan Journal of Ophthalmology
2. Gogate PM. Small incision cataract surgery: Complications and mini-review. Indian J Ophthalmol. 2009; 57: 45–9
3. Gogate PM, Kulkarni SR, Krishnaiah S, Deshpande RD, Joshi SA, Palimkar A, Deshpande MD. Safety and efficacy of phacoemulsification compared with manual small-incision cataract surgery by a randomized controlled clinical trial: sixweek results. Ophthalmology. 2005; 112: 869-74.
4. Mohammadpour M, Jafarinasab MR, Javadi MA. Outcomes of acute postoperative inflammation after cataract surgery. Eur J Ophthalmol. 2007; 17(1):20-8.
5. Çaça I, Şahin A, Cingü AK, Ari S, Alakuş F, Çinar Y. Effect of low molecular weight heparin (enoxaparin) on congenital cataract surgery. Int J Ophthalmol. 2012; 5: 596-9.
6. Kohnen T, Dick B, Hessemer V, Jacobi KW. The antiinflammatory effect of heparin-containing infusion solutions during phacoemulsification. Ophthalmology. 1995; 92: 297-302.
7. Hogan MJ, Kimura SJ, Thygeson P. Signs and symptoms of uveitis. 1 Anterior uveitis. Am J Ophthalmol. 1959; 47: 155–70.
8. Jongsareejit A, Wiriyaluppa C, Kongsap P, Phumipan S. Costeffectiveness analysis of manual small incision cataract surgery (MSICS) and phacoemulsification (PE). J Med Assoc Thai. 2012; 95: 212-20.
9. Haripriya A, Chang DF, Reena M, Shekhar M. Complication rates of phacoemulsification and manual small-incision cataract surgery at Aravind Eye Hospital. J Cataract Refract Surg. 2012; 38: 1360-9.
10. Parikshit MG. Small incision cataract surgery: Complications and mini-review. Indian J Ophthalmol. 2009; 57: 45–9.
11. Srikant KS, Sujata D, Suryasnath R. Blumenthal technique and its modification: The glory of anterior chamber maintainer. Indian J Ophthalmol. 2010; 58: 86.
12. Zaman M, Qadir A, Maooz, Shah I, Rehman I, Farooq T. Cataract a nigra (black cataract): a challenging task made easy with sutureless manual extracapsular cataract extraction. J ayub med coll abbottabad. 2011; 23: 108-10.
13. Xia XP, Lu DY, Wang LT. A clinical study of inhibition of secondary cataract with heparin. J Chung Hua Yen Ko Tsa Chih. 1994; 30: 405-7.
14. Kohnen T, Hessemer V, Koch DD, Jacobi KW. Effect of heparin in irrigating solution on inflammation following small incision cataract surgery. J Cataract Refract Surg. 1998; 24: 23743.
15. Kruger A, Amon M, Formanek CA, Schild G, Kolodjaschna J, Schauersberger J. Effect of heparin in the irrigation solution on postoperative inflammation and cellular reaction on the intraocular lens surface. J Cataract Refract Surg. 2002; 28: 87–92.
16. Dada T. Intracameral heparin in pediatric cataract surgery. J Cataract Refract Surg. 2003; 29: 1056. 17. Wilson ME, Trivedi RH. Low molecular-weight heparin in the intraocular irrigating solution in pediatric cataract and intraocular lens surgery. Am J Opthalmol. 2006; 141: 537–8.
18. Koraszewska-Matuszewska B, Samochowiec-Donocik E, Pieczara E, Flilipek E. Heparin-surface-modified PMMA intraocular lenses in children in early and late follow up. Klin Oczna. 2003; 105: 273-6. 19. Bayramlar H, Totan Y, Borazan M. Heparin in the intraocular irrigating solution in pediatric cataract surgery. J Cataract Refract Surg. 2004; 30: 2163–9.
20. Ihsan Ç, Alparslan Ş, Abdullah KC, Şeyhmus A, Fuat A, Yasin Ç. Effect of low molecular weight heparin (enoxaparin) on congenital cataract surgery. Int J Ophthalmol. 2012; 5: 596–9.